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A high GSH:GSSG ratio signals strong cellular health and acts as a biomarker for oxidative stress

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Yang Y, Sharma R, Zimniak P, Awasthi YC (2002) Role of class glutathione S -transferases as antioxidant enzymes in rodent tissues

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The important pathways involved in the KEGG pathway were neuroactive ligand-receptor interaction (hsa04080), PI3K-Akt signaling pathway (hsa04151), calcium signaling pathway (hsa04020), cAMP signaling pathway (hsa04024), MAPK signaling pathway (hsa04010), Ras signaling pathway (hsa04014), serotonergic synapse (hsa04726), and pathways of neurodegenerationmultiple diseases (hsa05022), Rap1 signaling pathway (hsa04015) and Alzheimers disease (hsa05010)